胃肠肿瘤中心二病区科主任、外科教研室副主任、主任医师、副教授、博士生导师、肿瘤学博士。现任CJCR杂志编辑部主任、中国抗癌协会期刊出版专委会主任委员、中国抗癌协会胃癌专业委员会委员。主要从事胃肠肿瘤的外科及相关研究工作，追踪国际肿瘤治疗前沿，参与消化道肿瘤治疗的众多新领域。特长于胃肠道肿瘤的根治手术、腹腔镜微创手术、早期胃癌功能保留手术、低位直肠保肛等术式。追求手术的微创与精细，注重患者神经功能保护及生活质量。对胃肠道手术有透悟的理解和娴熟的技术。主攻胃肠肿瘤的基础及临床转化研究。如胃癌免疫微环境图谱、胃癌淋巴结转移免疫微环境特点刻画、早期胃癌淋巴结转移特点及预测模型构建、胃癌的免疫治疗研究等。近5年作为通讯/并列通讯作者指导发表多篇有重要影响的学术论文。参与/承担多个国家级研究项目，如国家自然科学基金重大研究计划、国家自然科学基金面上项目、扬帆计划临床技术创新项目等。作为共同主编或副主编，出版了《普通外科疾病诊治思路》、《肿瘤组织标本库常用技术手册》、《Bethesda临床肿瘤学手册》等专著或译著。

近5年代表性论文：

1. Zheng L#, Qin S#, Si W#, Wang A, Xing B, Gao R, Ren X, Wang L, Wu X, Zhang J, Wu N, Zhang N, Zheng H, Ouyang H, Chen K, Bu Z*, Hu X*, Ji J*, Zhang Z*. Pan-cancer single-cell landscape of tumor-infiltrating T cells. Science,374(6574):abe6474.

2. Cheng S#, Li Z#, Gao R, Xing B, Gao Y, Yang Y, Qin S, Zhang L, Ouyang H, Du P, Jiang L, Zhang B, Yang Y, Wang X, Ren X, Bei JX, Hu X, Bu Z*, Ji J*, Zhang Z*. A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells. Cell,184 (3): 792-809.

3. Anqiang Wang#, Zhongwu Li#, Meng Wang#, Shuqin Jia#, Jiahu Chen , Ke Ji , Xin Ji , Xianglong Zong, Xiaojiang Wu, Ji Zhang, Ziyu Li, Lianhai Zhang, Ying Hu, Zhaode Bu*, Qi Zheng*, Jiafu Ji*. Molecular Characteristics of Synchronous Multiple Gastric Cancer. Theranostics,10(12):5489-5500.

4. He Q#, Chen J#, Zhou K#, Jin C#, Wang A, Ji K, Ji X, Zhang J, Wu X, Li X, Bu Z*, Ji J*. Effect of Additional Trastuzumab in Neoadjuvant and Adjuvant Treatment for Patients with Resectable HER2-Positive Gastric Cancer. Ann Surg Oncol,28(8): 4413-4422.

5. Wei J#, Zhang Y#, Liu Y, Wang A, Fan B, Fu T, Jia Z, He L, Ji K, Ji X, Wu X, Zhang J, Li Z, Zhang L, Bu Z*, Ji J*. Construction and Validation of a Risk-Scoring Model that Preoperatively Predicts Lymph Node Metastasis in Early Gastric Cancer Patients. Ann Surg Oncol,28(11): 6665-6672.

6. Liu Z#, Wang A#, Pu Y, Li Z, Xue R, Zhang C, Xiang X, E JY, Bu Z*, Bai F*, Ji J*. Genomic and transcriptomic profiling of hepatoid adenocarcinoma of the stomach. Oncogene,40 (38): 5705-5717.

7. Ji X, Bu ZD, Li ZY, Wu AW, Zhang LH, Zhang J, Wu XJ, Zong XL, Li SX, Shan F, Jia ZY, Ji JF. Prognostic significance of the total number of harvested lymph nodes for lymph node-negative gastric cancer patients. BMC Cancer,2017;17(1):558.

8. Zhang Y#, Liu Y#, Zhang J, Wu X, Ji X, Fu T, Li Z, Wu Q, Bu Z*, Ji J*. Construction and external validation of a nomogram that predicts lymph node metastasis in early gastric cancer patients using preoperative parameters. Chin J Cancer Res,30(6):623-632.